Version 5.4
Mus musculus Protein: Prdx6
Summary
InnateDB Protein IDBP-132605.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Prdx6
Protein Name peroxiredoxin 6
Synonyms 1-cysPrx; 9430088D19Rik; AA690119; aiPLA2; Aop2; Aop2-rs3; Brp-12; CC26; CP-3; GPx; Ltw-4; Ltw4; Lvtw-4; mKIAA0106; NSGP; NSGPx; ORF06; Prdx5; Prdx6-rs3;
Species Mus musculus
Ensembl Protein ENSMUSP00000050703
InnateDB Gene IDBG-201492 (Prdx6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 40 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004601 peroxidase activity
GO:0016209 antioxidant activity
GO:0016491 oxidoreductase activity
GO:0051920 peroxiredoxin activity
Biological Process
GO:0000302 response to reactive oxygen species
GO:0032060 bleb assembly
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:894320
InterPro IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
IPR012336 Thioredoxin-like fold
IPR013740 Redoxin
IPR019479 Peroxiredoxin, C-terminal
PFAM PF00578
PF13098
PF13192
PF13462
PF13905
PF08534
PF10417
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z0Y2
UniProt Splice Variant
Entrez Gene 11758
UniGene
RefSeq
MGI ID
MGI Symbol Prdx6
OMIM
CCDS
HPRD
IMGT
EMBL AC115751
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca