Version 5.4
Mus musculus Protein: Tmem18
Summary
InnateDB Protein IDBP-132608.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmem18
Protein Name transmembrane protein 18
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000050729
InnateDB Gene IDBG-132606 (Tmem18)
Protein Structure
UniProt Annotation
Function Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC) (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Nucleus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003677 DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0016477 cell migration
Cellular Component
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID MGI:2387176
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3TUD9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 211986
UniGene Mm.397290
RefSeq NP_742046
MGI ID
MGI Symbol Tmem18
OMIM
CCDS CCDS49043
HPRD
IMGT
EMBL AK133493 AK160817 AK166323 AK170496 BC024093
GenPept AAH24093 BAE21685 BAE36032 BAE38705 BAE41835

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca