InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ZNF622

Summary

InnateDB Protein

IDBP-13263.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ZNF622

Protein Name

zinc finger protein 622

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000310042

InnateDB Gene

IDBG-13259 (ZNF622)

Protein Structure

UniProt Annotation

Function

May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:11802789}. Nucleus {ECO:0000269PubMed:11802789}.

Disease Associations

Tissue Specificity

Expressed in lung, kidney, spleen, liver and brain with lowest expression in kidney. {ECO:0000269PubMed:11802789}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	40 [view]
Protein-Protein	40 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0033674	positive regulation of kinase activity
GO:0043065	positive regulation of apoptotic process
GO:0043410	positive regulation of MAPK cascade
GO:0046330	positive regulation of JNK cascade