Version 5.4
Mus musculus Protein: Psmd6
Summary
InnateDB Protein IDBP-132717.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Psmd6
Protein Name proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
Synonyms 2400006A19Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000022256
InnateDB Gene IDBG-132715 (Psmd6)
Protein Structure
UniProt Annotation
Function Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 75 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 75 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0022624 proteasome accessory complex
Protein Structure and Domains
PDB ID MGI:1913663
InterPro IPR000717 Proteasome component (PCI) domain
IPR019585 26S proteasome, regulatory subunit Rpn7
PFAM PF01399
PF10602
PRINTS
PIRSF
SMART SM00088
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99JI4
PhosphoSite PhosphoSite-Q99JI4
TrEMBL
UniProt Splice Variant
Entrez Gene 66413
UniGene Mm.27591
RefSeq NP_079826
MGI ID
MGI Symbol Psmd6
OMIM
CCDS CCDS26824
HPRD
IMGT
EMBL AJ252147 AK010287 BC006869
GenPept AAH06869 BAB26823 CAC34579

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca