Version 5.4
Mus musculus Protein: Prm2
Summary
InnateDB Protein IDBP-132739.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prm2
Protein Name protamine 2
Synonyms AI528784; Prm-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000047925
InnateDB Gene IDBG-132737 (Prm2)
Protein Structure
UniProt Annotation
Function Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.
Subcellular Localization Nucleus. Chromosome.
Disease Associations
Tissue Specificity Testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006997 nucleus organization
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0030261 chromosome condensation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:97766
InterPro IPR000492 Protamine 2, PRM2
PFAM PF00841
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P07978
PhosphoSite PhosphoSite-
TrEMBL Q545M0
UniProt Splice Variant
Entrez Gene 19119
UniGene
RefSeq NP_032959
MGI ID
MGI Symbol Prm2
OMIM
CCDS CCDS27955
HPRD
IMGT
EMBL AK005729 BC049612 CH466521 M16456 M27501 X07626 X14004 Z47352
GenPept AAA39981 AAA39986 AAH49612 BAB24208 CAA30473 CAA32170 CAA87411 EDK97326

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca