Version 5.4
Mus musculus Protein: Rmi2
Summary
InnateDB Protein IDBP-132796.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rmi2
Protein Name RIKEN cDNA A630055G03 gene
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000042676
InnateDB Gene IDBG-132794 (Rmi2)
Protein Structure
UniProt Annotation
Function Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. The complex is therefore essential for the stability, localization, and function of complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress- induced nuclear foci and mitotic phosphorylation of BLM (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Note=Colocalizes with BLM at nuclear DNA repair foci. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003677 DNA binding
Biological Process
GO:0006260 DNA replication
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2685383
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UPE3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 223970
UniGene Mm.487573
RefSeq NP_001156404
MGI ID
MGI Symbol Rmi2
OMIM
CCDS CCDS49761
HPRD
IMGT
EMBL AK080331 AK143588
GenPept BAE25452 BAE43370

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca