Version 5.4
Mus musculus Protein: Fam110c
Summary
InnateDB Protein IDBP-132807.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fam110c
Protein Name family with sequence similarity 110, member C
Synonyms 9030611O19Rik; AU019489;
Species Mus musculus
Ensembl Protein ENSMUSP00000041563
InnateDB Gene IDBG-132805 (Fam110c)
Protein Structure
UniProt Annotation
Function May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}. Nucleus {ECO:0000250}. Note=Colocalizes with microtubules during interphase. Detected at the mitotic spindle poles. Colocalizes with AKT1 at the cell cortex (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043014 alpha-tubulin binding
Biological Process
GO:0030335 positive regulation of cell migration
GO:0051897 positive regulation of protein kinase B signaling
GO:0060491 regulation of cell projection assembly
Cellular Component
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005815 microtubule organizing center
GO:0005874 microtubule
GO:0005938 cell cortex
Protein Structure and Domains
PDB ID MGI:1918813
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VE94
PhosphoSite PhosphoSite-Q8VE94
TrEMBL
UniProt Splice Variant
Entrez Gene 104943
UniGene Mm.248938
RefSeq NP_082104
MGI ID
MGI Symbol Fam110c
OMIM
CCDS CCDS25860
HPRD
IMGT
EMBL AK018545 AK160079 BC019466 BC085288
GenPept AAH19466 AAH85288 BAB31266 BAE35611

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca