Version 5.4
| Mus musculus Protein: Txndc11 | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-132898.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Txndc11 | ||||||
| Protein Name | thioredoxin domain containing 11 | ||||||
| Synonyms | 2810408E11Rik; AI427833; EFP1; Txdc11; | ||||||
| Species | Mus musculus | ||||||
| Ensembl Protein | ENSMUSP00000041113 | ||||||
| InnateDB Gene | IDBG-132896 (Txndc11) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation (By similarity). {ECO:0000250}. | ||||||
| Subcellular Localization | Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | |||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | MGI:1923620 | ||||||
| InterPro |
IPR012336
Thioredoxin-like fold IPR013766 Thioredoxin domain |
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| PFAM |
PF13098
PF13192 PF13462 PF13905 PF00085 |
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| PRINTS | |||||||
| PIRSF | |||||||
| SMART | |||||||
| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | Q8K2W3 | ||||||
| PhosphoSite | PhosphoSite-Q8K2W3 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 106200 | ||||||
| UniGene | Mm.445578 | ||||||
| RefSeq | NP_598866 | ||||||
| MGI ID | |||||||
| MGI Symbol | Txndc11 | ||||||
| OMIM | |||||||
| CCDS | CCDS27960 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AK029166 BC019564 BC029643 | ||||||
| GenPept | AAH19564 AAH29643 BAC26333 | ||||||