Version 5.4
Mus musculus Protein: Olah
Summary
InnateDB Protein IDBP-133124.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Olah
Protein Name oleoyl-ACP hydrolase
Synonyms AI607300; E230009B14Rik; Thedc1;
Species Mus musculus
Ensembl Protein ENSMUSP00000027955
InnateDB Gene IDBG-133122 (Olah)
Protein Structure
UniProt Annotation
Function In fatty acid biosynthesis chain termination and release of the free fatty acid product is achieved by hydrolysis of the thio ester by a thioesterase I, a component of the fatty acid synthetase complex. The chain length of the released fatty acid is usually C16. However, in the mammary glands of non-ruminant mammals, and in the uropygial gland of certain waterfowl there exists a second thioesterase which releases medium-chain length fatty acids (C8 to C2) (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004320 oleoyl-[acyl-carrier-protein] hydrolase activity
GO:0016295 myristoyl-[acyl-carrier-protein] hydrolase activity
GO:0016296 palmitoyl-[acyl-carrier-protein] hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0009058 biosynthetic process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:2139018
InterPro IPR001031 Thioesterase
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00975
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R197
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 99035
UniGene Mm.13808
RefSeq XP_006497634
MGI ID
MGI Symbol Olah
OMIM
CCDS CCDS15647
HPRD
IMGT
EMBL AK087571 AK136031 BC025001
GenPept AAH25001 BAC39932 BAE22784

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca