InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Oxsm

Summary

InnateDB Protein

IDBP-133187.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Oxsm

Protein Name

3-oxoacyl-ACP synthase, mitochondrial

Synonyms

4933425A18Rik; C80494;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000022311

InnateDB Gene

IDBG-133185 (Oxsm)

Protein Structure

UniProt Annotation

Function

May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

Biological Process

GO:0006633	fatty acid biosynthetic process
GO:0006637	acyl-CoA metabolic process
GO:0008152	metabolic process
GO:0051790	short-chain fatty acid biosynthetic process
GO:0051792	medium-chain fatty acid biosynthetic process

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

MGI:1918397

InterPro

IPR014030 Beta-ketoacyl synthase, N-terminal
IPR014031 Beta-ketoacyl synthase, C-terminal
IPR016039 Thiolase-like
IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain

PFAM

PF00109
PF02801

PRINTS

PIRSF

PIRSF000447

SMART

SM00825

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt