InnateDB Protein
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IDBP-133300.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Pgcp
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Protein Name
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plasma glutamate carboxypeptidase
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Synonyms
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1190003P12Rik; 2610034C17Rik; Hls2; Lal-1; Pgcp;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000039046
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InnateDB Gene
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IDBG-133298 (Pgcp)
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Protein Structure
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Function |
Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor (By similarity). {ECO:0000250}.
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Subcellular Localization |
Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}. Lysosome {ECO:0000250}. Secreted {ECO:0000250}. Note=Secretion is stimulated by TSH/thyroid- stimulating hormone, INS/insulin and SST/somatostatin. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1889205
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InterPro |
IPR002933
Peptidase M20
IPR007484
Peptidase M28
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PFAM |
PF01546
PF04389
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9WVJ3
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
54381
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UniGene |
Mm.487325
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RefSeq |
NP_788262
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MGI ID |
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MGI Symbol |
Cpq
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OMIM |
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CCDS |
CCDS27414
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HPRD |
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IMGT |
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EMBL |
AF009513
AF107835
AK032972
AK075686
AK135096
AK137164
AK152139
AK152145
BC037067
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GenPept |
AAC17945
AAD43215
AAH37067
BAC28105
BAC35891
BAE22419
BAE23259
BAE30978
BAE30982
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