Version 5.4
Mus musculus Protein: Cpa3
Summary
InnateDB Protein IDBP-133539.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cpa3
Protein Name carboxypeptidase A3, mast cell
Synonyms MC-CPA; mMC-CPA;
Species Mus musculus
Ensembl Protein ENSMUSP00000001921
InnateDB Gene IDBG-133537 (Cpa3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasmic vesicle, secretory vesicle. Note=Secretory granules.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 0
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004180 carboxypeptidase activity
GO:0004181 metallocarboxypeptidase activity
GO:0008233 peptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0002002 regulation of angiotensin levels in blood
GO:0006508 proteolysis
Cellular Component
GO:0030133 transport vesicle
Protein Structure and Domains
PDB ID MGI:88479
InterPro IPR000834 Peptidase M14, carboxypeptidase A
IPR003146 Proteinase inhibitor, carboxypeptidase propeptide
IPR009020 Proteinase inhibitor, propeptide
PFAM PF00246
PF02244
PRINTS PR00765
PIRSF
SMART SM00631
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P15089
PhosphoSite PhosphoSite-
TrEMBL Q542E3
UniProt Splice Variant
Entrez Gene 12873
UniGene Mm.470340
RefSeq NP_031779
MGI ID
MGI Symbol Cpa3
OMIM
CCDS CCDS17262
HPRD
IMGT
EMBL AK088906 CH466530 J05118
GenPept AAA37369 BAC40646 EDL34896

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca