Version 5.4
Mus musculus Protein: Frmd4a
Summary
InnateDB Protein IDBP-133662.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Frmd4a
Protein Name FERM domain containing 4A
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000089079
InnateDB Gene IDBG-133660 (Frmd4a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0030674 protein binding, bridging
Biological Process
GO:0090162 establishment of epithelial cell polarity
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005923 tight junction
Protein Structure and Domains
PDB ID MGI:1919850
InterPro IPR000299 FERM domain
IPR018979 FERM, N-terminal
IPR018980 FERM, C-terminal PH-like domain
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR019750 Band 4.1 family
IPR021774 Protein of unknown function DUF3338
IPR029071 Ubiquitin-related domain
PFAM PF09379
PF09380
PF00373
PF11819
PRINTS PR00935
PIRSF
SMART SM00295
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BIE6
PhosphoSite PhosphoSite-Q8BIE6
TrEMBL Q3TB04
UniProt Splice Variant
Entrez Gene 209630
UniGene Mm.487653
RefSeq NP_766063
MGI ID
MGI Symbol Frmd4a
OMIM
CCDS CCDS15656
HPRD
IMGT
EMBL AB093292 AK082365 AK171532 AL807832 AL845441 AL928947 AL928978 AL935139 AL954325 BC058672
GenPept AAH58672 BAC38478 BAC41475 BAE42510 CAM46014 CAM46015 CAM46270 CAM46271

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca