Version 5.4
Mus musculus Protein: Slc22a20
Summary
InnateDB Protein IDBP-133834.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc22a20
Protein Name solute carrier family 22 (organic anion transporter), member 20
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000049473
InnateDB Gene IDBG-133832 (Slc22a20)
Protein Structure
UniProt Annotation
Function Organic anion transporter that mediates the uptake of estrone sulfate. Inhibited by probenecid, propionate, 2- methylbutyrate, 3-methylbutyrate, benzoate, heptanoate and 2- ethylhaxanoate. May act as an odorant transporter. {ECO:0000269PubMed:16478971, ECO:0000269PubMed:17094945}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Highly expressed in olfactory mucosa. Weakly expressed in testis. Not detected in heart, spleen, lung, kidney or brain. {ECO:0000269PubMed:15369770, ECO:0000269PubMed:17094945}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008514 organic anion transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0015711 organic anion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2685809
InterPro IPR005828 General substrate transporter
IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain
PFAM PF00083
PF07690
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80UJ1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 381203
UniGene
RefSeq NP_941052
MGI ID
MGI Symbol Slc22a20
OMIM
CCDS CCDS29486
HPRD
IMGT
EMBL AY194118 BC046588
GenPept AAH46588 AAO91751

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca