Mus musculus Protein: Ube2e2
Summary
InnateDB Protein IDBP-133880.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ube2e2
Protein Name ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000075495
InnateDB Gene IDBG-133878 (Ube2e2)
Protein Structure
UniProt Annotation
Function Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination (By similarity). Catalyzes the ISGylation of influenza A virus NS1 protein (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 64 interaction(s) predicted by orthology.
Predicted by orthology
Total 64 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005524 ATP binding
GO:0016881 acid-amino acid ligase activity
GO:0042296 ISG15 ligase activity
Biological Process
GO:0032020 ISG15-protein conjugation
GO:0070534 protein K63-linked ubiquitination
GO:0070936 protein K48-linked ubiquitination
GO:0070979 protein K11-linked ubiquitination
Cellular Component
Protein Structure and Domains
PDB ID MGI:2384997
InterPro IPR000608 Ubiquitin-conjugating enzyme, E2
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
PFAM PF00179
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91W82
PhosphoSite PhosphoSite-Q91W82
TrEMBL D3YW10
UniProt Splice Variant
Entrez Gene 218793
UniGene Mm.408538
RefSeq XP_006518072
MGI ID
MGI Symbol Ube2e2
OMIM
CCDS CCDS26838
HPRD
IMGT
EMBL AC118006 AC121296 AC132459 BC016265
GenPept AAH16265