InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sephs1

Summary

InnateDB Protein

IDBP-133928.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sephs1

Protein Name

selenophosphate synthetase 1

Synonyms

1110046B24Rik; AA589574; AI505014; AW111620; SELD; SPS; SPS1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000027973

InnateDB Gene

IDBG-133926 (Sephs1)

Protein Structure

UniProt Annotation

Function

Synthesizes selenophosphate from selenide and ATP.

Subcellular Localization

Cell membrane {ECO:0000250}. Nucleus membrane {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004756	selenide, water dikinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0008150	biological_process
GO:0016310	phosphorylation

Cellular Component

GO:0005886	plasma membrane
GO:0031965	nuclear membrane

Protein Structure and Domains

PDB ID

MGI:1923580

InterPro

IPR000728 AIR synthase related protein, N-terminal domain
IPR004536 Selenide water dikinase
IPR010918 AIR synthase-related protein, C-terminal domain
IPR016188 PurM, N-terminal-like

PFAM

PF00586
PF02769

PRINTS

PIRSF

PIRSF036407

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BH69