InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pex3

Summary

InnateDB Protein

IDBP-134307.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pex3

Protein Name

peroxisomal biogenesis factor 3

Synonyms

1700014F15Rik; 2810027F19Rik; 2900010N04Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000019945

InnateDB Gene

IDBG-134305 (Pex3)

Protein Structure

UniProt Annotation

Function

Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.

Subcellular Localization

Peroxisome membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Identified in all tissues analyzed, with the strongest expression in liver and in testis.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008289	lipid binding
GO:0046983	protein dimerization activity

Biological Process

GO:0007031	peroxisome organization
GO:0016557	peroxisome membrane biogenesis
GO:0045046	protein import into peroxisome membrane

Cellular Component

GO:0005634	nucleus
GO:0005777	peroxisome
GO:0005778	peroxisomal membrane
GO:0005779	integral component of peroxisomal membrane
GO:0005783	endoplasmic reticulum
GO:0005829	cytosol
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0032994	protein-lipid complex
GO:0043231	intracellular membrane-bounded organelle
GO:0043234	protein complex