InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cwc15

Summary

InnateDB Protein

IDBP-134444.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cwc15

Protein Name

CWC15 homolog (S. cerevisiae)

Synonyms

0610040D20Rik; 2900052N06Rik; c11orf5; Ed1; mED1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000004200

InnateDB Gene

IDBG-134442 (Cwc15)

Protein Structure

UniProt Annotation

Function

Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	4 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003723	RNA binding
GO:0005515	protein binding

Biological Process

GO:0000398	mRNA splicing, via spliceosome
GO:0008150	biological_process

Cellular Component

GO:0005634	nucleus
GO:0005681	spliceosomal complex
GO:0071013	catalytic step 2 spliceosome

Protein Structure and Domains

PDB ID

MGI:1913320

InterPro

IPR006973 Pre-mRNA-splicing factor Cwf15/Cwc15

PFAM

PF04889

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9JHS9

PhosphoSite

PhosphoSite-Q9JHS9

TrEMBL

UniProt Splice Variant

Entrez Gene

66070

UniGene

Mm.395571

RefSeq

NP_075642

MGI ID

MGI Symbol

Cwc15

OMIM

CCDS

CCDS22823

HPRD

IMGT

EMBL

AJ250394 AK002864 AK003202 AK003591 AK003834 AK145249 AK167776 AK168365 AY842452 BC004726

GenPept

AAH04726 AAW32096 BAB22414 BAB22638 BAB22880 BAB23026 BAE26327 BAE39808 BAE40300 CAB96547