Version 5.4
| Mus musculus Protein: Gpr126 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-134532.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Gpr126 | ||||||||
| Protein Name | G protein-coupled receptor 126 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000043055 | ||||||||
| InnateDB Gene | IDBG-134530 (Gpr126) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Orphan receptor. May be required for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Signals probably through G-proteins to transiently elevate cAMP levels (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed at high levels in the heart and somite during embryogenesis and in adult lung. {ECO:0000269PubMed:15189448}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1916151 | ||||||||
| InterPro |
IPR000203
GPS motif IPR000832 GPCR, family 2, secretin-like IPR000859 CUB domain IPR001759 Pentaxin IPR001879 GPCR, family 2, extracellular hormone receptor domain IPR008985 Concanavalin A-like lectin/glucanases superfamily IPR017981 GPCR, family 2-like |
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| PFAM |
PF01825
PF00002 PF00431 PF00354 PF02793 |
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| PRINTS |
PR00249
PR00895 |
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| PIRSF | |||||||||
| SMART |
SM00303
SM00042 SM00159 SM00008 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q6F3F9 | ||||||||
| PhosphoSite | PhosphoSite-Q6F3F9 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 215798 | ||||||||
| UniGene | Mm.440142 | ||||||||
| RefSeq | NP_001002268 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Gpr126 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS35848 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AB183545 BC046534 | ||||||||
| GenPept | AAH46534 BAD27570 | ||||||||