InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Prss16

Summary

InnateDB Protein

IDBP-134853.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Prss16

Protein Name

protease, serine, 16 (thymus)

Synonyms

AI448615; TSSP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000006341

InnateDB Gene

IDBG-134851 (Prss16)

Protein Structure

UniProt Annotation

Function

Protease that may play a role in T-cell development.

Subcellular Localization

Cytoplasmic vesicle. Note=Vesicular, either lysosomal or endosomal.

Disease Associations

Tissue Specificity

Expressed predominantly in cortical thymic epithelial cells, with highest expression around vessels and the thymic capsule.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008236	serine-type peptidase activity

Biological Process

GO:0006508

proteolysis

Cellular Component

GO:0005764	lysosome
GO:0005768	endosome
GO:0016023	cytoplasmic membrane-bounded vesicle

Protein Structure and Domains

PDB ID

MGI:1859181

InterPro

IPR008758 Peptidase S28
IPR029058 Alpha/Beta hydrolase fold

PFAM

PF05577

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9QXE5

PhosphoSite

PhosphoSite-Q9QXE5

TrEMBL

Q5SZ30

UniProt Splice Variant

Entrez Gene

54373

UniGene

Mm.402203

RefSeq

NP_062302

MGI ID

MGI Symbol

Prss16

OMIM

CCDS

CCDS26303

HPRD

IMGT

EMBL

AJ131775 AK088019 BC125481 BC131955 CH466561

GenPept

AAI25482 AAI31956 BAC40100 CAB66137 EDL32616