Version 5.4
Mus musculus Protein: Atg2a
Summary
InnateDB Protein IDBP-134909.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atg2a
Protein Name ATG2 autophagy related 2 homolog A (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000046412
InnateDB Gene IDBG-134907 (Atg2a)
Protein Structure
UniProt Annotation
Function Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion (By similarity). Mediates the intracellular lifestyle of Cryptococcus neoformans by supporting infection. {ECO:0000250, ECO:0000269PubMed:21698225}.
Subcellular Localization Preautophagosomal structure membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Lipid droplet {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006914 autophagy
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005811 lipid particle
GO:0034045 pre-autophagosomal structure membrane
Protein Structure and Domains
PDB ID MGI:1916291
InterPro IPR015412 Autophagy-related, C-terminal
PFAM PF09333
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6P4T0
PhosphoSite PhosphoSite-Q6P4T0
TrEMBL
UniProt Splice Variant
Entrez Gene 329015
UniGene Mm.277384
RefSeq NP_919329
MGI ID
MGI Symbol Atg2a
OMIM
CCDS CCDS29500
HPRD
IMGT
EMBL AK129132 AK151782 BC022657 BC056482 BC063264
GenPept AAH22657 AAH56482 AAH63264 BAC97942 BAE30685

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca