InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rpl7

Summary

InnateDB Protein

IDBP-135046.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rpl7

Protein Name

ribosomal protein L7

Synonyms

Rpl7a; Surf-3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000071616

InnateDB Gene

IDBG-135044 (Rpl7)

Protein Structure

UniProt Annotation

Function

Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 113 interaction(s) predicted by orthology.

Experimentally validated
Total	26 [view]
Protein-Protein	26 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	113 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003729	mRNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006364	rRNA processing
GO:0006412	translation
GO:0042273	ribosomal large subunit biogenesis

Cellular Component

GO:0005634	nucleus
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit
GO:0030529	ribonucleoprotein complex
GO:0070062	extracellular vesicular exosome