Version 5.4
Mus musculus Protein: Tagap
Summary
InnateDB Protein IDBP-135080.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tagap
Protein Name T-cell activation Rho GTPase-activating protein
Synonyms 2610315E15Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000047431
InnateDB Gene IDBG-135078 (Tagap)
Protein Structure
UniProt Annotation
Function May function as a GTPase-activating protein. May play a role in transmission ratio distortion (TRD) in mouse, in which heterozygous males for t-locus transmit their t-carrying chromosome to 95% or more of their offspring. {ECO:0000269PubMed:16116428}.
Subcellular Localization
Disease Associations
Tissue Specificity Highly expressed in testis. {ECO:0000269PubMed:16116428}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005085 guanyl-nucleotide exchange factor activity
Biological Process
GO:0007165 signal transduction
GO:0043087 regulation of GTPase activity
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID MGI:3615484
InterPro IPR000198 Rho GTPase-activating protein domain
IPR008936 Rho GTPase activation protein
PFAM PF00620
PRINTS
PIRSF
SMART SM00324
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt B2RWW0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 72536
UniGene Mm.119680
RefSeq NP_666080
MGI ID
MGI Symbol Tagap
OMIM
CCDS CCDS28379
HPRD
IMGT
EMBL BC030886 BC039780 BC150728
GenPept AAH30886 AAH39780 AAI50729

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca