InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rnaset2a

Summary

InnateDB Protein

IDBP-135259.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rnaset2a

Protein Name

ribonuclease T2A

Synonyms

0610007O07Rik; 4833423A10Rik; 4930532K22Rik; C79750; RNASE6PL; Rnaset2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000095031

InnateDB Gene

IDBG-703071 (Rnaset2a)

Protein Structure

UniProt Annotation

Function

Has ribonuclease activity, with higher activity at acidic pH. May play a role in cellular RNA catabolism. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000250}. Endoplasmic reticulum lumen {ECO:0000250}. Lysosome lumen {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003723	RNA binding
GO:0004519	endonuclease activity
GO:0004540	ribonuclease activity
GO:0016787	hydrolase activity
GO:0033897	ribonuclease T2 activity

Biological Process

GO:0006401	RNA catabolic process
GO:0008150	biological_process
GO:0090501	RNA phosphodiester bond hydrolysis
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005739	mitochondrion
GO:0005764	lysosome
GO:0005788	endoplasmic reticulum lumen
GO:0043202	lysosomal lumen