InnateDB Protein
|
IDBP-135420.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Ywhaz
|
Protein Name
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
|
Synonyms
|
1110013I11Rik; 14-3-3zeta; AI596267; AL022924; AU020854;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000022894
|
InnateDB Gene
|
IDBG-135418 (Ywhaz)
|
Protein Structure
|
|
Function |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
|
Subcellular Localization |
Cytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes. {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 195 experimentally validated interaction(s) in this database.
They are also associated with 557 interaction(s) predicted by orthology.
Experimentally validated |
Total |
195
[view]
|
Protein-Protein |
195
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
557 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:109484
|
InterPro |
IPR000308
14-3-3 protein
IPR023410
14-3-3 domain
|
PFAM |
PF00244
|
PRINTS |
PR00305
|
PIRSF |
PIRSF000868
|
SMART |
SM00101
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P63101
|
PhosphoSite |
PhosphoSite-P63101
|
TrEMBL |
D3YXN6
|
UniProt Splice Variant |
|
Entrez Gene |
22631
|
UniGene |
Mm.3360
|
RefSeq |
NP_035870
|
MGI ID |
|
MGI Symbol |
Ywhaz
|
OMIM |
|
CCDS |
CCDS27432
|
HPRD |
|
IMGT |
|
EMBL |
AC138604
AK083368
AK145657
AK146800
AK150381
AK151900
AK162099
AK167128
BC050891
BC089334
D78647
D83037
D87660
U79231
|
GenPept |
AAC53254
AAH50891
AAH89334
BAA11464
BAA11751
BAA13421
BAC38887
BAE26570
BAE27442
BAE29512
BAE30783
BAE36724
BAE39275
|
|
|