InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ifnk

Summary

InnateDB Protein

IDBP-135678.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ifnk

Protein Name

interferon kappa

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000054273

InnateDB Gene

IDBG-135676 (Ifnk)

Protein Structure

UniProt Annotation

Function

May play a role in the regulation of immune cell function.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed at low levels in peritoneal macrophages. {ECO:0000269PubMed:12759458}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005125	cytokine activity
GO:0005126	cytokine receptor binding
GO:0005132	type I interferon receptor binding

Biological Process

GO:0002250	adaptive immune response
GO:0002286	T cell activation involved in immune response
GO:0002323	natural killer cell activation involved in immune response
GO:0006355	regulation of transcription, DNA-templated
GO:0006952	defense response
GO:0006959	humoral immune response
GO:0009615	response to virus
GO:0019221	cytokine-mediated signaling pathway
GO:0030183	B cell differentiation
GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
GO:0042100	B cell proliferation
GO:0043330	response to exogenous dsRNA
GO:0045087	innate immune response
GO:0045343	regulation of MHC class I biosynthetic process
GO:0051607	defense response to virus