InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Abt1

Summary

InnateDB Protein

IDBP-135745.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Abt1

Protein Name

activator of basal transcription 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000045888

InnateDB Gene

IDBG-135743 (Abt1)

Protein Structure

UniProt Annotation

Function

Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes.

Subcellular Localization

Nucleus {ECO:0000269PubMed:10648625}. Nucleus, nucleolus {ECO:0000269PubMed:10648625}.

Disease Associations

Tissue Specificity

Ubiquitously expressed. {ECO:0000269PubMed:10648625}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0021522	spinal cord motor neuron differentiation