Version 5.4
Mus musculus Protein: Defb41
Summary
InnateDB Protein IDBP-135900.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Defb41
Protein Name defensin beta 41
Synonyms 9230102D03Rik; Bd-41; Defb16;
Species Mus musculus
Ensembl Protein ENSMUSP00000085811
InnateDB Gene IDBG-135898 (Defb41)
Protein Structure
UniProt Annotation
Function Has bactericidal activity (By similarity). May play a role in the antimicrobial protection of sperm and urogenital tract epithelia. {ECO:0000250, ECO:0000269PubMed:16023745}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity Epididymis-specific. Expressed mainly in the proximal caput. {ECO:0000269PubMed:16023745}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0042742 defense response to bacterium
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:1924923
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C1G4
PhosphoSite PhosphoSite-Q8C1G4
TrEMBL
UniProt Splice Variant
Entrez Gene 77673
UniGene Mm.99530
RefSeq NP_898947
MGI ID
MGI Symbol Defb41
OMIM
CCDS CCDS48226
HPRD
IMGT
EMBL AK020304 BK005412 DQ012027
GenPept AAY59763 BAC25620 DAA05561

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca