InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Olig3

Summary

InnateDB Protein

IDBP-135920.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Olig3

Protein Name

oligodendrocyte transcription factor 3

Synonyms

Bhlhb7; bHLHe20;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000057106

InnateDB Gene

IDBG-135918 (Olig3)

Protein Structure

UniProt Annotation

Function

May determine the distinct specification program of class A neurons in the dorsal part of the spinal cord and suppress specification of class B neurons. {ECO:0000269PubMed:15769945}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00981, ECO:0000269PubMed:11091082, ECO:0000269PubMed:11960707}.

Disease Associations

Tissue Specificity

Weakly expressed, mainly in non-neural tissues. {ECO:0000269PubMed:15489334}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001106	RNA polymerase II transcription corepressor activity
GO:0003677	DNA binding
GO:0046983	protein dimerization activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated
GO:0010468	regulation of gene expression
GO:0021520	spinal cord motor neuron cell fate specification
GO:0021522	spinal cord motor neuron differentiation
GO:0097476	spinal cord motor neuron migration