InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Zfp828

Summary

InnateDB Protein

IDBP-136019.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Zfp828

Protein Name

zinc finger protein 828

Synonyms

AA675043; AI116001; D8Ertd457e; D8Ertd569e; mKIAA1802; Zfp828; Znf828;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000057270

InnateDB Gene

IDBG-136017 (Zfp828)

Protein Structure

UniProt Annotation

Function

Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0031134	sister chromatid biorientation
GO:0034501	protein localization to kinetochore
GO:0035372	protein localization to microtubule
GO:0051315	attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation