InnateDB Protein
|
IDBP-136240.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Hist1h1d
|
Protein Name
|
histone cluster 1, H1d
|
Synonyms
|
H1.3; H1D; H1f3; H1s-4;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000044395
|
InnateDB Gene
|
IDBG-136238 (Hist1h1d)
|
Protein Structure
|
|
Function |
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Nucleus. Chromosome. Note=Mainly localizes in euchromatin. {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
7
[view]
|
Protein-Protein |
7
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:107502
|
InterPro |
IPR005818
Linker histone H1/H5, domain H15
IPR005819
Histone H5
|
PFAM |
PF00538
|
PRINTS |
PR00624
|
PIRSF |
|
SMART |
SM00526
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P43277
|
PhosphoSite |
PhosphoSite-P43277
|
TrEMBL |
Q149Z9
|
UniProt Splice Variant |
|
Entrez Gene |
14957
|
UniGene |
Mm.247046
|
RefSeq |
NP_663759
|
MGI ID |
|
MGI Symbol |
Hist1h1d
|
OMIM |
|
CCDS |
CCDS26346
|
HPRD |
|
IMGT |
|
EMBL |
AK054269
AY158906
BC117045
BC119173
CH466561
U62923
Z38128
|
GenPept |
AAB05799
AAI17046
AAI19174
AAO06217
BAC35711
CAA86288
EDL32557
|
|
|