Version 5.4
Mus musculus Protein: Wdr44
Summary
InnateDB Protein IDBP-136262.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wdr44
Protein Name WD repeat domain 44
Synonyms 2610034K17Rik; 9130203L06; RAB11BP; RPH11;
Species Mus musculus
Ensembl Protein ENSMUSP00000099193
InnateDB Gene IDBG-136258 (Wdr44)
Protein Structure
UniProt Annotation
Function Downstream effector for RAB11. May be involved in vesicle recycling (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytosol. Cytoplasm, perinuclear region. Endosome membrane. Golgi apparatus, trans-Golgi network. Note=Colocalized with RAB11 along microtubules oriented toward lamellipodia. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0010008 endosome membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:1919654
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PRINTS PR00320
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NVE8
PhosphoSite PhosphoSite-Q6NVE8
TrEMBL Q8BZS8
UniProt Splice Variant
Entrez Gene 72404
UniGene Mm.423
RefSeq XP_006527764
MGI ID
MGI Symbol Wdr44
OMIM
CCDS CCDS40892
HPRD
IMGT
EMBL AK033628 AK088885 AK139877 BC049191 BC068151
GenPept AAH49191 AAH68151 BAC28399 BAC40631 BAE24167

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca