Version 5.4
Mus musculus Protein: Ubtfl1
Summary
InnateDB Protein IDBP-136268.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ubtfl1
Protein Name upstream binding transcription factor, RNA polymerase I-like 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000096572
InnateDB Gene IDBG-136266 (Ubtfl1)
Protein Structure
UniProt Annotation
Function Essential for proliferation of the inner cell mass and trophectodermal cells in peri-implantation development. {ECO:0000269PubMed:19915186}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:19915186}. Nucleus {ECO:0000255PROSITE-ProRule:PRU00267, ECO:0000269PubMed:19915186}. Note=Mainly cytoplasmic from the 4- cell stage to the morula stage. Becomes nuclear at the blastocyst stage. In ES cells, found in both the nucleus and the cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003677 DNA binding
Biological Process
GO:0001832 blastocyst growth
GO:0007566 embryo implantation
GO:0010468 regulation of gene expression
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:3588290
InterPro IPR009071 High mobility group box domain
PFAM PF00505
PF09011
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3USZ2
PhosphoSite PhosphoSite-Q3USZ2
TrEMBL
UniProt Splice Variant
Entrez Gene 546118
UniGene Mm.380138
RefSeq
MGI ID
MGI Symbol Ubtfl1
OMIM
CCDS CCDS40540
HPRD
IMGT
EMBL AK139937 AK163257 BC139141 BC145822 CH466522
GenPept AAI39142 AAI45823 BAE24188 BAE37262 EDL25044 EDL25045

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca