InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Klf10

Summary

InnateDB Protein

IDBP-136309.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Klf10

Protein Name

Kruppel-like factor 10

Synonyms

AI115143; EGR[a]; Egral; Gdnfif; mGIF; Tieg; TIEG-1; Tieg1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000073690

InnateDB Gene

IDBG-136307 (Klf10)

Protein Structure

UniProt Annotation

Function

Transcriptional repressor involved in the regulation of cell growth. Inhibits cell growth.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	20 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0030282	bone mineralization
GO:0035019	somatic stem cell maintenance
GO:0045672	positive regulation of osteoclast differentiation
GO:1901653	cellular response to peptide

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:1101353

InterPro

IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like

PFAM

PF00096

PRINTS

PIRSF

SMART

SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O89091

PhosphoSite

PhosphoSite-O89091

TrEMBL

UniProt Splice Variant

Entrez Gene

21847

UniGene

RefSeq

NP_038720

MGI ID

MGI Symbol

Klf10

OMIM

CCDS

CCDS27438

HPRD

IMGT

EMBL

AF049879 AF049880 AF064088 BC003316

GenPept

AAC16734 AAC77796 AAC77797 AAH03316