Version 5.4
Mus musculus Protein: Pacrg
Summary
InnateDB Protein IDBP-136317.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pacrg
Protein Name PARK2 co-regulated
Synonyms 1700008H23Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000044376
InnateDB Gene IDBG-136315 (Pacrg)
Protein Structure
UniProt Annotation
Function Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005488 binding
Biological Process
GO:0007286 spermatid development
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005929 cilium
GO:0044297 cell body
GO:0097225 sperm midpiece
Protein Structure and Domains
PDB ID MGI:1916560
InterPro IPR016024 Armadillo-type fold
IPR019399 Parkin co-regulated protein
PFAM PF10274
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DAK2
PhosphoSite PhosphoSite-
TrEMBL Q0VB91
UniProt Splice Variant
Entrez Gene 69310
UniGene Mm.18889
RefSeq NP_081308
MGI ID
MGI Symbol Pacrg
OMIM
CCDS CCDS28388
HPRD
IMGT
EMBL AC109609 AF549257 AK005771 BC120740 CH466619
GenPept AAI20741 AAO16245 AAP94052 BAB24230 EDL02079

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca