Mus musculus Protein: Hist1h2bn | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||
InnateDB Protein | IDBP-136347.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | Hist1h2bn | ||||||||||
Protein Name | histone cluster 1, H2bn | ||||||||||
Synonyms | |||||||||||
Species | Mus musculus | ||||||||||
Ensembl Protein | ENSMUSP00000089301 | ||||||||||
InnateDB Gene | IDBG-703246 (Hist1h2bn) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||||||||||
Subcellular Localization | Nucleus. Chromosome. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | |||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||||||||
Gene Ontology | |||||||||||
Molecular Function |
|
||||||||||
Biological Process |
|
||||||||||
Cellular Component |
|
||||||||||
Protein Structure and Domains | |||||||||||
PDB ID | MGI:2448407 | ||||||||||
InterPro |
IPR000558
Histone H2B IPR003958 Transcription factor CBF/NF-Y/archaeal histone IPR007125 Histone core IPR009072 Histone-fold |
||||||||||
PFAM |
PF00808
PF00125 |
||||||||||
PRINTS |
PR00621
|
||||||||||
PIRSF | |||||||||||
SMART |
SM00427
|
||||||||||
TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | P10853 | ||||||||||
PhosphoSite | PhosphoSite-P10853 | ||||||||||
TrEMBL | A0JLV3 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 319187 | ||||||||||
UniGene | Mm.261677 | ||||||||||
RefSeq | NP_835508 | ||||||||||
MGI ID | |||||||||||
MGI Symbol | Hist1h2bn | ||||||||||
OMIM | |||||||||||
CCDS | CCDS26294 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | AL589651 AL589879 AL590614 AY158927 AY158929 AY158932 AY158935 BC115792 U62669 X05862 | ||||||||||
GenPept | AAB04762 AAI15793 AAO06237 AAO06239 AAO06242 AAO06245 CAA29290 CAI24103 CAI24111 CAI25462 CAI25467 CAI26130 | ||||||||||