Version 5.4
Mus musculus Protein: Slc7a14
Summary
InnateDB Protein IDBP-136392.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc7a14
Protein Name solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000088803
InnateDB Gene IDBG-136390 (Slc7a14)
Protein Structure
UniProt Annotation
Function May be involved in arginine transport. {ECO:0000250}.
Subcellular Localization Lysosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Exhibits a punctated pattern in the cytoplasm, which partially ovelaps with lysosomes. {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in retina, brain and spinal cord. In the retina, expressed in the inner nuclear layer and photoreceptor layer (at protein level). {ECO:0000269PubMed:24670872}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0015171 amino acid transmembrane transporter activity
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006810 transport
GO:0010923 negative regulation of phosphatase activity
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3040688
InterPro IPR004841 Amino acid permease/ SLC12A domain
PFAM PF00324
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BXR1
PhosphoSite PhosphoSite-Q8BXR1
TrEMBL
UniProt Splice Variant
Entrez Gene 241919
UniGene Mm.444101
RefSeq NP_766449
MGI ID
MGI Symbol Slc7a14
OMIM
CCDS CCDS17291
HPRD
IMGT
EMBL AK044448 AK173217 BC061928
GenPept AAH61928 BAC31925 BAD32495

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca