InnateDB Protein
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IDBP-136507.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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B4galt1
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Protein Name
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UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
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Synonyms
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B-1,4-GalT; B-1,4-GalT1; b4Gal-T1; beta-1,4-GalT; beta-1,4-GalT1; beta4Gal-T1; GalT; Ggtb; Ggtb2;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000030121
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InnateDB Gene
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IDBG-136505 (B4galt1)
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Protein Structure
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Function |
The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions, as those occurring during development and egg fertilization, by binding to specific oligosaccharide ligands on opposing cells or in the extracellular matrix.
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Subcellular Localization |
Isoform Long: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Cell surface. Note=Found in trans cisternae of Golgi.Isoform Short: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Found in trans cisternae of Golgi.Processed beta-1,4-galactosyltransferase 1: Secreted. Note=Soluble form found in body fluids.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated |
Total |
5
[view]
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Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
1
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
8 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:95705
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InterPro |
IPR003859
Beta-1,4-galactosyltransferase
IPR027791
Galactosyltransferase, C-terminal
IPR029044
Nucleotide-diphospho-sugar transferases
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PFAM |
PF02709
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PRINTS |
PR02050
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P15535
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q6LDL0
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UniProt Splice Variant |
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Entrez Gene |
14595
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UniGene |
Mm.15622
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RefSeq |
NP_071641
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MGI ID |
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MGI Symbol |
B4galt1
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OMIM |
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CCDS |
CCDS18051
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HPRD |
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IMGT |
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EMBL |
AK132970
AK154393
AK167322
BC026824
BC053006
CH466538
D00314
J03880
L16840
M27917
M27918
M27919
M27920
M27921
M27922
M36289
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GenPept |
AAA37294
AAA37295
AAA37297
AAA58744
AAA58745
AAA62340
AAH26824
AAH53006
BAA00216
BAE21450
BAE32556
BAE39424
EDL05427
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