Mus musculus Protein: Rbm17
Summary
InnateDB Protein IDBP-136580.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rbm17
Protein Name RNA binding motif protein 17
Synonyms 2700027J02Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000041831
InnateDB Gene IDBG-136578 (Rbm17)
Protein Structure
UniProt Annotation
Function Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000375 RNA splicing, via transesterification reactions
GO:0000380 alternative mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1924188
InterPro IPR000467 G-patch domain
IPR003954 RNA recognition motif domain, eukaryote
IPR016967 Splicing factor, SPF45
PFAM PF01585
PRINTS
PIRSF PIRSF031066
SMART SM00443
SM00361
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8JZX4
PhosphoSite PhosphoSite-Q8JZX4
TrEMBL A2AP40
UniProt Splice Variant
Entrez Gene 76938
UniGene Mm.182769
RefSeq NP_690037
MGI ID
MGI Symbol Rbm17
OMIM
CCDS CCDS15684
HPRD
IMGT
EMBL AF083384 AL831794 BC034896
GenPept AAC64085 AAH34896 CAM13750