Version 5.4
| Mus musculus Protein: Hist1h2ab | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-136992.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Hist1h2ab | ||||||||
| Protein Name | histone cluster 1, H2ab | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000077477 | ||||||||
| InnateDB Gene | IDBG-136990 (Hist1h2ab) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||||||||
| Subcellular Localization | Nucleus. Chromosome. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2448306 | ||||||||
| InterPro |
IPR002119
Histone H2A IPR003958 Transcription factor CBF/NF-Y/archaeal histone IPR007125 Histone core IPR009072 Histone-fold |
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| PFAM |
PF00808
PF00125 |
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| PRINTS |
PR00620
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| PIRSF | |||||||||
| SMART |
SM00414
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | P22752 | ||||||||
| PhosphoSite | PhosphoSite-P22752 | ||||||||
| TrEMBL | B2RVF0 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 665433 | ||||||||
| UniGene | Mm.423402 | ||||||||
| RefSeq | NP_783591 | ||||||||
| MGI ID | 2F8N | ||||||||
| MGI Symbol | Hist1h2ab | ||||||||
| OMIM | |||||||||
| CCDS | CCDS26364 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK028026 AK033518 AK145443 AK146846 AL589651 AL589879 AL590388 AL590614 AL592149 AY158909 AY158912 AY158913 AY158914 AY158915 AY158917 AY158918 AY158919 AY158920 BC058544 BC062251 BC065803 BC076498 BC090402 BC099406 BC110626 BC116373 BC117110 BC119295 BC119297 BC125248 BC127164 BC133661 BC134370 BC139479 BC146008 BC147161 BC147162 CH466561 M33988 M37736 U62669 X05862 | ||||||||
| GenPept | AAA37763 AAA37809 AAB04761 AAH58544 AAH62251 AAH65803 AAH76498 AAH90402 AAH99406 AAI10627 AAI16374 AAI17111 AAI19296 AAI19298 AAI25249 AAI27165 AAI33662 AAI34371 AAI39480 AAI46009 AAI47162 AAI47163 AAO06220 AAO06222 AAO06223 AAO06224 AAO06225 AAO06227 AAO06228 AAO06229 AAO06230 BAC25706 BAC28337 BAE26439 BAE27477 CAA29291 CAI24114 CAI24893 CAI25463 CAI25466 CAI25841 CAI26126 CAI26129 EDL32539 EDL32548 EDL32553 EDL32555 EDL32607 EDL32610 EDL32623 EDL32628 EDL32635 | ||||||||