InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lrrn3

Summary

InnateDB Protein

IDBP-137021.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lrrn3

Protein Name

leucine rich repeat protein 3, neuronal

Synonyms

NLRR-3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000043818

InnateDB Gene

IDBG-137019 (Lrrn3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed in the brain, in Stronger expression in the ventricular zone and anlage of thalamus, spinal cord, and dorsal root ganglion in E11-17 cerebellum and cerebral cortex in adults. {ECO:0000269PubMed:9011764}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0032403	protein complex binding

Biological Process

GO:0001934

positive regulation of protein phosphorylation

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0030131	clathrin adaptor complex

Protein Structure and Domains

PDB ID

MGI:106036

InterPro

IPR000372 Leucine-rich repeat-containing N-terminal
IPR000483 Cysteine-rich flanking region, C-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013151 Immunoglobulin

PFAM