Version 5.4
| Mus musculus Protein: Kcnk4 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-137167.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Kcnk4 | ||||||||
| Protein Name | potassium channel, subfamily K, member 4 | ||||||||
| Synonyms | MLZ-622; Tex40; TRAAK; TRAAKt; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000025908 | ||||||||
| InnateDB Gene | IDBG-137165 (Kcnk4) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Voltage insensitive, instantaneous, outwardly rectifying potassium channel. Outward rectification is reversed at high external K(+) concentrations. | ||||||||
| Subcellular Localization | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed in brain, spinal cord and eye. Not detected in heart, skeletal muscle, liver, lungs, kidney and testis. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1298234 | ||||||||
| InterPro |
IPR003092
Two pore domain potassium channel, TASK family IPR003280 Two pore domain potassium channel IPR003976 Two pore domain potassium channel, TREK IPR005821 Ion transport domain IPR008074 Two pore domain potassium channel, TRAAK IPR013099 Two pore domain potassium channel domain |
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| PFAM |
PF00520
PF07885 |
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| PRINTS |
PR01095
PR01333 PR01499 PR01691 |
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| PIRSF |
PIRSF038061
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| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | O88454 | ||||||||
| PhosphoSite | PhosphoSite-O88454 | ||||||||
| TrEMBL | Q0VD85 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 16528 | ||||||||
| UniGene | Mm.12894 | ||||||||
| RefSeq | NP_032457 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Kcnk4 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS29511 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF056492 BC119784 CH466612 | ||||||||
| GenPept | AAC40181 AAI19785 EDL33262 | ||||||||