InnateDB Protein
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IDBP-137182.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ttyh1
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Protein Name
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tweety homolog 1 (Drosophila)
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Synonyms
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4930459B04Rik; 6330408P11Rik; tty;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000078384
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InnateDB Gene
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IDBG-137176 (Ttyh1)
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Protein Structure
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Function |
Probable chloride channel. Isoform 3 may be a Ca(2+)- independent and swelling-activated chloride channel, possibly involved in regulation of cell volume. May be involved in cell adhesion (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Restricted mainly to neural tissues. Strongly expressed in brain and eye. {ECO:0000269PubMed:17116230}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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|
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Molecular Function |
Accession |
GO Term |
GO:0005509
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calcium ion binding
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GO:0072320
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volume-sensitive chloride channel activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1889007
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InterPro |
IPR006990
Tweety
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PFAM |
PF04906
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9D3A9
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PhosphoSite |
PhosphoSite-Q9D3A9
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
57776
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UniGene |
Mm.474056
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RefSeq |
NP_001001454
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MGI ID |
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MGI Symbol |
Ttyh1
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OMIM |
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CCDS |
CCDS51970
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HPRD |
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IMGT |
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EMBL |
AB162929
AF190699
AF190991
AK015486
AK018148
AK043998
AK048413
AK049903
BC046310
BC065694
DQ104403
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GenPept |
AAG02615
AAG15842
AAH46310
AAH65694
AAZ06803
BAB29865
BAB31094
BAC31730
BAC33329
BAC33980
BAD20188
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