Version 5.4
Mus musculus Protein: Defb38
Summary
InnateDB Protein IDBP-137665.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Defb38
Protein Name defensin beta 38
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000067553
InnateDB Gene IDBG-137663 (Defb38)
Protein Structure
UniProt Annotation
Function Synthetic Defb38 kills both Gram-negative (E.coli and P.aeruginosa) and Gram-positive (E.faecium) bacteria. {ECO:0000269PubMed:14718547}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Only expressed in epididymis (caput, corpus and cauda). {ECO:0000269PubMed:14718547}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006952 defense response
GO:0008150 biological_process
GO:0042742 defense response to bacterium
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:2672972
InterPro IPR001855 Beta defensin type
PFAM PF00711
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TNV7
PhosphoSite PhosphoSite-
TrEMBL Q05A65
UniProt Splice Variant
Entrez Gene 360212
UniGene Mm.271558
RefSeq NP_898857
MGI ID
MGI Symbol Defb38
OMIM
CCDS CCDS40248
HPRD
IMGT
EMBL AJ575424 AJ578471 BC125388 BC125390 CH466566
GenPept AAI25389 AAI25391 CAE01397 CAE17668 EDL22225

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca