Version 5.4
Mus musculus Protein: Ncr1
Summary
InnateDB Protein IDBP-137682.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ncr1
Protein Name natural cytotoxicity triggering receptor 1
Synonyms Ly94; NKp46;
Species Mus musculus
Ensembl Protein ENSMUSP00000006792
InnateDB Gene IDBG-137680 (Ncr1)
Protein Structure
UniProt Annotation
Function Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Selectively expressed by NK cells. {ECO:0000269PubMed:10092106}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1336212
InterPro IPR003599 Immunoglobulin subtype
PFAM
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C567
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 17086
UniGene Mm.240231
RefSeq NP_034876
MGI ID
MGI Symbol Ncr1
OMIM
CCDS CCDS20734
HPRD
IMGT
EMBL AJ223765 AK079401 BC042788 BC115364
GenPept AAH42788 AAI15365 BAC37635 CAB39169

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca