InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tbpl1

Summary

InnateDB Protein

IDBP-137710.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tbpl1

Protein Name

TATA box binding protein-like 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000093470

InnateDB Gene

IDBG-137708 (Tbpl1)

Protein Structure

UniProt Annotation

Function

Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes (By similarity). Seems to also mediate the transcription of NF1. Does not bind the TATA box. {ECO:0000250, ECO:0000269PubMed:15767669, ECO:0000269PubMed:9889269}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Ubiquitously expressed. {ECO:0000269PubMed:16412700, ECO:0000269PubMed:9889269}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding

Biological Process

GO:0001675	acrosome assembly
GO:0006235	dTTP biosynthetic process
GO:0006352	DNA-templated transcription, initiation
GO:0007283	spermatogenesis
GO:0007289	spermatid nucleus differentiation