InnateDB Protein
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IDBP-137794.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Slc17a4
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Protein Name
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solute carrier family 17 (sodium phosphate), member 4
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000021769
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InnateDB Gene
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IDBG-137792 (Slc17a4)
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Protein Structure
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Function |
Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro) (By similarity). {ECO:0000250}.
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Subcellular Localization |
Apical cell membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein. Note=Apical in the intestinal brush border. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2442850
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InterPro |
IPR011701
Major facilitator superfamily
IPR016196
Major facilitator superfamily domain, general substrate transporter
IPR020846
Major facilitator superfamily domain
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PFAM |
PF07690
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-Q5NCM1
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
319848
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UniGene |
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RefSeq |
XP_006516762
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MGI ID |
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MGI Symbol |
Slc17a4
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
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GenPept |
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