Version 5.4
Mus musculus Protein: Fgl2
Summary
InnateDB Protein IDBP-137823.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fgl2
Protein Name fibrinogen-like protein 2
Synonyms AI385601; musfiblp;
Species Mus musculus
Ensembl Protein ENSMUSP00000046131
InnateDB Gene IDBG-137821 (Fgl2)
Protein Structure
UniProt Annotation
Function Converts prothrombin to thrombin.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Constitutively expressed in cytotoxic T-cells.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 0
Protein-DNA 6 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0019835 cytolysis
Cellular Component
GO:0005576 extracellular region
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:103266
InterPro IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
IPR009053 Prefoldin
PFAM PF00147
PRINTS
PIRSF
SMART SM00186
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P12804
PhosphoSite PhosphoSite-
TrEMBL Q71V87
UniProt Splice Variant
Entrez Gene 14190
UniGene Mm.466072
RefSeq NP_032039
MGI ID
MGI Symbol Fgl2
OMIM
CCDS CCDS19103
HPRD
IMGT
EMBL AF025817 AF025818 AF036762 AK036402 BC028893 CH466586 M15761 M16238 S78773
GenPept AAA37624 AAB34823 AAB88814 AAB88815 AAB92553 AAH28893 BAC29413 EDL03209

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca