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InnateDB Protein
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IDBP-137889.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Trpt1
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Protein Name
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tRNA phosphotransferase 1
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Synonyms
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AU079016; AW045591; Tpt1; Tpt1h;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000085555
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InnateDB Gene
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IDBG-137887 (Trpt1)
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Protein Structure
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| Function |
Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate. {ECO:0000269PubMed:9826666}.
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
3 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0000215
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tRNA 2'-phosphotransferase activity
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GO:0008665
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2'-phosphotransferase activity
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GO:0016772
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transferase activity, transferring phosphorus-containing groups
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| Biological Process |
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GO:0006388
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tRNA splicing, via endonucleolytic cleavage and ligation
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GO:0045859
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regulation of protein kinase activity
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| Cellular Component |
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| PDB ID |
MGI:1333115
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| InterPro |
IPR002745
Phosphotransferase KptA/Tpt1
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| PFAM |
PF01885
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q8K3A2
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
107328
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| UniGene |
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| RefSeq |
NP_705825
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| MGI ID |
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| MGI Symbol |
Trpt1
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| OMIM |
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| CCDS |
CCDS50375
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| HPRD |
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| IMGT |
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| EMBL |
BC027575
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| GenPept |
AAH27575
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Version 5.4