Version 5.4
Mus musculus Protein: 1110017D15Rik
Summary
InnateDB Protein IDBP-137926.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol 1110017D15Rik
Protein Name RIKEN cDNA 1110017D15 gene
Synonyms Cbe1; Smrp1;
Species Mus musculus
Ensembl Protein ENSMUSP00000030152
InnateDB Gene IDBG-137924 (1110017D15Rik)
Protein Structure
UniProt Annotation
Function May be involved in differentiation or function of ciliated cells (By similarity). May play a role in spermatogenesis. {ECO:0000250, ECO:0000269PubMed:18163442}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000269PubMed:18163442}. Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Localizes to the manchette in elongating spermatids. Predominantly perinuclear in bronchial epithelial cells but also detected in the nucleus in some primary epithelial cells and in a number of cell lines.
Disease Associations
Tissue Specificity Isoforms 1 is testis-specific where it is expressed exclusively in germ cells (at protein level). Isoform 2 is testis-specific. Isoform 3 and isoform 4 are expressed in both lung and testis. {ECO:0000269PubMed:18163442, ECO:0000269PubMed:19213785}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0043014 alpha-tubulin binding
Biological Process
GO:0007283 spermatogenesis
GO:0030154 cell differentiation
GO:0043623 cellular protein complex assembly
Cellular Component
GO:0002177 manchette
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:1920971
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2MH31
PhosphoSite PhosphoSite-Q2MH31
TrEMBL
UniProt Splice Variant
Entrez Gene 73721
UniGene Mm.45614
RefSeq NP_082900
MGI ID
MGI Symbol 1110017D15Rik
OMIM
CCDS CCDS38717
HPRD
IMGT
EMBL AB231294 AK003742 AL831723 DQ873295 DQ873296
GenPept ABI35956 ABI35957 BAB22974 BAE78528

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca